Wound-healing coating with multiple effect patented by the Institute of Chemistry

The team at the Department of High Molecular and Organoelement Compounds is headed by Professor Irina Galkina.

“Our research group is engaged in the synthesis of new compounds with high biological activity and the development of pharmaceutical compositions for veterinary medicine based on them. In December 2023, our group received a patent for the invention. We created a wound coating for animals, which has not only wound healing, as previously existed, but also antimicrobial and antifungal properties. It can be used in the treatment of minor injuries as well as in surgical practice,” explains Senior Lecturer Semyon Romanov. “Our active ingredient is injected into collagen sponge “Meturacol”, designed for covering wounds (it is a white plate with a thickness from 7 to 13 mm, having a porous structure and relief surface), which contains methyluracil in its composition, accelerating the process of cell tissue regeneration. Our synthesized broad-spectrum complex includes three components: 4,6-dinitro-5,7-dichlorobenzofuroxan, n-hexadecyltriphenylphosphonium bromide, chlorhexidine bigluconate. It destroys both fungi, gram-positive bacteria and gram-negative bacteria, allows to significantly reduce the time of wound healing in animals. The effectiveness of many currently available substances which are used to imbue the “Meturacol” sponge is quite low, so the dressings created on their basis may have a negative impact on the wound surface and surrounding tissues.”

The chemist emphasizes that the patented coating doesn’t contain any of the most widely used antibacterial medications, which makes it useful when dealing with antibiotic-resistant infections.

The invention now has to go through animal tests, licensing, and certification.